Nashville native James Denton, who originally attended college on a basketball scholarship, wasn't bitten by the acting bug until he was 28. He landed the role of George Gibbs in a Nashville production of Our Town , got fine reviews, but thought there was a more solid career in selling advertising. He did that in Tennessee and then in North Carolina for four years before taking off for Chicago to become a professional actor. Denton soon was accepted as one of Chicago's brightest stars. After earning a key casting when the “Untouchables” series came to town to film, he was drawn to Los Angeles, where his strong theatre reputation preceded him. Soon, Denton was locked in with choice turns in film, on TV and on the stage.
As one of the stars of the Golden Globe and SAG Award-winning "Desperate Housewives," Denton started building his Hollywood career with performances in such films as "Primary Colors," "Face/Off" and "That Old Feeling," but soon off-beat roles in adventurous TV series were claiming his time. In 1997 Denton landed the role of the eerily sociopathic Mr. Lyle on NBC's hit drama, "The Pretender." The series' multi-year run was followed by "The Pretender" television films, "Pretender 2001" and "Pretender: The Island of The Haunted." In 2001 Denton was cast by ABC to star opposite Kim Delaney in Steven Bochco's "Philly," a critically acclaimed but short-lived series. Denton's growing reputation quickly led to a new series, casting him as a top player in this nation's homeland security community, Special Agent Jon Kilmer on "Threat Matrix." In addition to his starring roles on TV, his guest appearances include "JAG," "Slider," "Dark Skies," "Two Guys and a Girl," "Ally McBeal" and "The West Wing." His latest feature film “Grace Unplugged” was released in the fall of 2013.
Acting is serious work for the handsome and athletic Denton, and his training with some of Chicago’s best teachers pointed him in that direction. His first role there was as Stanley Kowalski in A Streetcar Named Desire, and his last was the terrorist in the French farce, Lapin, Lapin. He was a company member of the Griffin Theatre and at the Strawdog Theatre Ensemble. He added a steady string of roles and accolades to his quickly growing list, including one of the leads in the world premiere of Flesh and Blood, performing in and composing the music for The Night Hank Williams Died, and his portrayal of Kentucky preacher C.C. Showers in The Diviners, which gained him a coveted Joseph Jefferson Best Actor nomination. For these performances, Denton was listed as one of Chicago's hottest actors by Screen Magazine. In Los Angeles, he appeared in the premieres of Asylum at the Court Theatre, Locked Up Down Shorty's at the Powerhouse Theatre, and In Walked Monk at the Hudson Theatre.
Denton’s musical endeavor, Band From TV (BFTV) was formed when Greg Grunberg (“Heroes”), Hugh Laurie (“House”) and Bob Guiney (“The Bachelor”) decided to band their musical interests together to raise money for charity. The Band, which also includes Jesse Spencer (“House”), Scott Grimes (“ER,” “Band of Brothers”) and Adrian Pasdar (“Heroes”), plays several shows around the country to raise money for charity. Since their inception, BFTV has raised almost two million dollars for various causes supported by the band.\
James Denton also starts in the Hallmark Channel Original series, "Cedar Cove."