If you're going to be out of town for a while, shut off the water to the house and to the water heater, and drain the system. If possible blow air into the system to get all of the water out. This will prevent water freezing in the pipes, and expanding. Main thing I want to stress is: unless you are an expert – call your plumber. However, I’ve got some great ways to keep your pipes from freezing as well as what to do if they do freeze.